Corrected sodium calculator for hyperglycemia

Enter measured sodium and blood glucose to see what the sodium would be at a normal glucose of 100 mg/dL (5.6 mmol/L), by both the Katz and the Hillier correction. It is an estimate for information, not a diagnosis.

mmol/L
Glucose units
mg/dL
Corrected sodium, Katz (1.6)134.8 mmol/L
Corrected sodium, Hillier (2.4)137.2 mmol/L
Glucose in mmol/L
22.2 mmol/L

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How to use it

  1. Enter the measured sodium in mmol/L (mEq/L).
  2. Pick the glucose units and enter the blood glucose.
  3. Read the corrected sodium by Katz and by Hillier.

The formulas

With glucose in mg/dL:

  • Katz: corrected Na = Na + 1.6 × (glucose − 100) / 100
  • Hillier: corrected Na = Na + 2.4 × (glucose − 100) / 100

Glucose in mmol/L is multiplied by 18.016 to get mg/dL first.

Worked example

Sodium 130 mmol/L, glucose 400 mg/dL (22.2 mmol/L). Excess glucose 300 mg/dL, that is 3 × 100:

  • Katz: 130 + 1.6 × 3 = 134.8 mmol/L
  • Hillier: 130 + 2.4 × 3 = 137.2 mmol/L

A sodium that looked low is in or near the normal range once glucose is taken into account.

Tips

  • Use sodium and glucose from the same blood sample.
  • A high corrected sodium during treatment of diabetic ketoacidosis or a hyperosmolar state means water loss that needs attention.
  • This is an estimate for information, not a diagnosis or a treatment decision.

Frequently asked questions

Why does high glucose lower sodium?

Glucose draws water out of the cells into the blood, which dilutes the sodium. The measured value looks low although the body's sodium has not changed. The corrected value estimates the sodium once glucose comes back to normal.

Katz or Hillier: which should I use?

Katz (1973) adds 1.6 mmol/L for every 100 mg/dL of glucose above 100. Hillier (1999) found a larger effect, 2.4 mmol/L per 100 mg/dL, especially at very high glucose. Many clinicians look at both; the calculator shows them side by side.

Is mEq/L the same as mmol/L for sodium?

Yes. Sodium carries a single charge, so 1 mEq/L equals 1 mmol/L.

What if glucose is below 100 mg/dL?

The correction then goes slightly the other way and is so small that it does not matter clinically. The formula is meant for high glucose.

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